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A fuzzy rule-based decision support system for Duodopa treatment in Parkinson

Full text:  
Authors: Mobyen Uddin Ahmed, Jerker Westin (Högskolan Dalarna), Dag Nyholm (external), Mark Dougherty (Högskolan Dalarna), Torgny Groth (Uppsala University)
Source: SAIS 2006, p 45-50, Umeå, May 10-12, Editor(s):P. Eklund, M. Minock, H. Lindgren
 

Abstract

A decision support system (DSS) was implemented based on a fuzzy logic inference system (FIS) to provide assistance in dose alteration of Duodopa infusion in patients with advanced Parkinson’s disease, using data from motor state assessments and dosage. Three-tier architecture with an object oriented approach was used. The DSS has a web enabled graphical user interface that presents alerts indicating non optimal dosage and states, new recommendations, namely typical advice with typical dose and statistical measurements. One data set was used for design and tuning of the FIS and another data set was used for evaluating performance compared with actual given dose. Overall goodness-of-fit for the new patients (design data) was 0.65 and for the ongoing patients (evaluation data) 0.98. User evaluation is now ongoing. The system could work as an assistant to clinical staff for Duodopa treatment in advanced Parkinson’s disease.
 

BibTeX entry

@inproceedings{Uddin_1161:2006,
   author = {Mobyen Uddin Ahmed and Jerker Westin and Dag Nyholm and Mark Dougherty and Torgny Groth},
   title = {A fuzzy rule-based decision support system for Duodopa treatment in Parkinson},
   booktitle = {SAIS 2006},
   month = {May},
   year = {2006},
   pages = {45-50},
   editor = {P. Eklund, M. Minock, H. Lindgren},
   url = {http://www.mrtc.mdh.se/index.php?choice=publications&id=1161},
}

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